Haemophilia is inherited genetic fatal diseases. In Haemophilia person’s condition become severe due to excessive bleeding . in Haemophilia body loses its ability to make clot factor and when sudden injury occur that maybe minor cut accident wound etc Injuries need to stop bleeding ultimately. Joint bleeding can cause permanent damage while brain bleeding causes a severe headache.
Haemophilia generally is of two types:
1. Haemophilia A – It occurs due to lack of clotting factor VIII generally in males. affects about 1 in 5,000–10,000 males at birth. In majority cases, it is inherited as an X-linked recessive trait arises from spontaneous mutations, Factor VIII medication can be used to treat bleeding.
2. Haemophilia B – It occurs due to excess clotting factor IX. It affects about 1 in 5,000–10,000 males at birth. Haemophilia B causes easy bruising and bleeding, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (haemophilia A). Haemophilia B was first recognized in 1952.
⦁ Internal or external bleeding episodes, which are called “bleeds”.
⦁ In children, frequent and large bruises and haematomas from frequent bumps and falls as they learn to walk.
⦁ Swelling and bruising from bleeding in the joints, soft tissue, and muscles may also occur.
⦁ Internal bleeding is common.
It is a genetic disease with no causes. Haemophilia has featured prominently in European royalty and thus is sometimes known as ‘the royal disease’. Queen Victoria passed inherited haemophilia to her and, through two of her daughters, to various royals across the continent, including the royal families of Spain, Germany, and Russia.
It can be cured before during or after birth if there are genetic evidence of this diseases .children with no inheritance of this diseases then also it occurs, in this case, it can be treated when the child is on walking or crawling stage.